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Pulmonary arterial hypertension (PAH)


Pulmonary arterial hypertension (PAH)


Pulmonary arterial hypertension (PAH) is a rare and severe disease that continues to progress over time.[1] It is caused by the narrowing of the pulmonary arteries, which connect the right side of the heart to the lungs.[2] PAH may occur with no identifiable cause or may be associated with one or more underlying conditions.[3] As PAH develops, blood flow through the pulmonary arteries is restricted and the right side of the heart becomes enlarged due to the increased strain of pumping blood through the lungs.[4]

PAH Home - Intro
Pathophysiology of PAH

While the exact cause of PAH is uncertain, a clearer picture of the underlying pathological mechanisms is emerging.

Diagnosis of PAH

Clinical guidelines set out the diagnostic pathway so patients can be referred and treated as quickly as possible.

Treatment of PAH

Modern treatments can significantly improve patients’ symptoms and slow the rate of clinical deterioration.

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Discover our resources

Diagnostic tools, expert opinion videos and educational aids to help you identify, assess and manage your PAH patients.

Get in touch with our team

Question or remark related PAH, the studies or our products? Click below to get in touch with a product specialist or medical science liaison.

Discover our portfolio

For over 20 years, we have been working with HCP’s in order to help transform the management of PAH with our treatments.

References

D’Alonzo GE et al. Ann Intern Med 1991; 115:343–349.
Gaine S. JAMA 2000; 284:3160–3168.
Galiè N et al. Eur Heart J 2016; 37:67–119.
Vonk Noordegraaf A et al. Eur Respir J 2019; 53:1801900.
CP-308773 - April 2022